Cayenne (Capsicum) is used for conditions of the heart and blood vessels including poor circulation, excessive blood clotting, high cholesterol, and preventing heart disease. It's ï»¿used for various problems with digestion including upset stomach, intestinal gas, stomach pain, diarrhea, and cramps.

Other uses include relief of toothache, seasickness, alcoholism, malaria, and fever.

Some people apply capsicum to the skin for pain caused by shingles, osteoarthritis, rheumatoid arthritis, and fibromyalgia. It is also used topically for nerve pain (neuropathy) associated with diabetes and HIV, other types of nerve pain (neuralgia), and back pain.